Exposure to Human Herpes Virus Type 6 Protects Against Allergic Asthma in Mice
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چکیده
Allergic diseases among children and youth are today one of the most common chronicle diseases in westernized countries, and the prevalence has increased dramatically during the last decades. The great increase in allergy prevalence is commonly explained by the hygiene hypothesis, postulating that a clean lifestyle increases the risk of developing allergy, and that exposure to microbes early in life may protect against allergic disease. The hygiene hypothesis was initially based on the observation that children that are more consistently exposed to infections, such as children from large families and those attending day care, are statistically less likely to develop atopic disease than e.g. first-born or single children [1]. However, it is not yet clear whether it is bacterial or viral exposure that plays the main inhibitory role during the development of allergic manifestations.
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تاریخ انتشار 2010